Jai Ho Tamil Version Video Song Download
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Due to differing requirements in different regions and different interpretation of biopharmaceutical classifications, drugmakers may end up following different approaches in different regions to developing generic drugs. Using the biopharmaceutics classification system, drugs fall into four classes based on the aqueous solubility and intestinal permeability of the drug substance. ICH says it expects the guideline to be adopted in May 2019. The guideline is being developed to harmonize an approach to biopharmaceutics classification of drugs and provide recommendations for when bioequivalence studies can be waived. Bcs classification of drug. Biopharmaceutics Classification System (BCS) Class I: high solubility, high permeability Class II: low solubility, high permeability Class III: high solubility, low permeability Class IV: low solubility, low permeability According to ICH, guidelines in the US, EU, Japan, Canada and from the World Health Organization (WHO) provide slightly different recommendations on bioequivalence and biowaivers.
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